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These include NAD(P)H:quinone reductase-1 ( NQO1 ), haemoxygenase-1 ( HO-1 ), glutamate-cysteine ligase ( GCL ), glutathione-S-transferase ( GST ), glutathione peroxidase ( GPX1 ), thioredoxin ( TXN ), thioredoxin reductase ( TXNRD1 ) [92], and PPAR- ( PPARG ) [136]

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In those cases, restoring healthy B12 levels may help the body function more smoothly

Animals were housed under standard conditions: ambient temperature maintained at 1628 C, relative humidity 3070%, and a 12-hour light/dark cycle with illumination intensity between 100 and 200 lx